CFTR SegCheck™ Kit v2.2

Cystic fibrosis (CF) diagnostic kit

Cystic fibrosis (CF) is an inherited genetic disorder caused by mutations in the CFTR gene. A disorder that causes the loss of regulation of proteins, which results in thick and sticky mucus in the respiratory, digestive, and genital tracts.

Lungs, digestive system, pancreas, liver and reproductive system are among the sensitive and vulnerable organs in this disease.

The CFTR SegCheck™ kit v2.2 has helped to diagnose cystic fibrosis in cases of consanguineous marriages and also has the ability to screen for early aneuploidy in chromosomes 13, 18, 21, X and Y in a short period of time. This kit is based on 15 markers, including 6 STR markers with high heterozygosity upstream and downstream of the CFTR gene, and 6 markers for the initial screening of common chromosomal disorders based on (QF-PCR) and an amylogenin marker (AMXY) with markers DX-TATC13/3 and SRY are for gender determination. The simultaneous analysis of these markers and the evaluation of the obtained haplotypes are used as a valuable auxiliary tool in prenatal diagnosis and determination of the carrier of cystic fibrosis disease and the screening of common aneuploidies.