HBA Gap Detection Kit

Alpha-Thalassemia is an inherited, autosomal recessive blood disorder that is caused by mutations in the alpha-globin genes.

The HBA Gap Detection Kit is designed to detect common and large deletions in the alpha-globin gene cluster in carriers and before the birth of alpha-thalassemia. It consists of 8 primers mixed in the kit, enabling rapid and accurate detection of common deletions in the alpha-globin gene cluster. Deletion mutations are assessed using the Multiplex gap-PCR method. This kit detects common deletion in middle east such as 3.7, 4.2, 20.5, and Med deletions. This kit contains all the necessary materials for PCR, including primers, buffer, and enzyme. The PCR result is visualized on 1-1.5% agarose gel and easily analyzable. It is recommended to use 1Kb ladder to precise detection of fragment sizes on the gel.