AneuQuick Max v2.2
Cat. No: KBC-110115کیت تشخیص مولکولی اختلالات عددی شایع کروموزومی(انیوپلوئیدی)
AneuQuick™ Max v2.2 Kit
AneuQuick™ Max v2.2 is a QF-PCR (Quantitative Fluorescent PCR) kit designed for the rapid detection of chromosomal aneuploidies involving chromosomes 13, 18, 21, X and Y. Using 33 highly informative STR markers in a single multiplex PCR reaction, the kit enables fast and reliable screening of the most common fetal chromosomal abnormalities, including Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), Patau syndrome (Trisomy 13), Turner syndrome (Monosomy X) and Klinefelter syndrome (47, XXY).
The kit is compatible with DNA extracted from peripheral blood, amniotic fluid, chorionic villus samples (CVS), tissue samples and cell-free DNA from amniotic fluid. AneuQuick™ Max v2.2 also works on KBC DBC™. Its optimized marker panel and streamlined workflow make it a practical solution for molecular genetics laboratories and prenatal testing facilities.
Key Features & Benefits
- Rapid detection of aneuploidies involving chromosomes 13, 18, 21, X and Y
- Based on Quantitative Fluorescent PCR (QF-PCR) technology
- Simultaneous amplification of 33 STR markers in a single multiplex PCR reaction
- Comprehensive chromosome coverage for confident result interpretation
- Includes segmental duplication markers to improve detection of Turner syndrome
- Compatible with a wide range of prenatal and clinical DNA sample types
- Designed for 6-dye fragment analysis
- Streamlined workflow with reduced hands-on time
- Suitable for molecular genetics, prenatal diagnosis and research laboratories
- Reliable and reproducible assay performance
AneuQuick™ Max v2.2 contains 33 carefully selected STR markers distributed across chromosomes 13, 18, 21, X and Y. The marker panel has been evaluated using thousands of DNA samples to ensure high heterozygosity and maximize the number of informative markers across different populations.
| Number of markers | |
| Chromosome 21 | 8 |
| Chromosome 18 | 7 |
| Chromosome 13 | 7 |
| X/Y | 2 |
| X chromosome | 8 |
| Y Chromosome | 2 |
In addition to conventional STR markers, the kit incorporates 7/X, 11/X and 18/X segmental duplication markers, providing improved assessment of X chromosome copy number and increasing confidence in the detection of Turner syndrome.
The AneuQuick™ family of QF-PCR kits has been developed to provide flexible solutions for rapid prenatal aneuploidy screening. Whether your laboratory requires a standard aneuploidy assay, expanded chromosome coverage, or simultaneous SMA detection, the AneuQuick™ portfolio offers a kit tailored to your workflow.
| Feature | AneuQuick v4.2 | AneuQuick Plus v2.2 | AneuQuick Extra v2.2 | AneuQuick Max v2.2 | AneuQuick Extra Plus v2.2 | AneuQuick Max Plus v2.2 |
| Total Markers | 27 | 29 | 33 | 33 | 35 | 35 |
| X markers | 7 | 7 | 8 | 8 | 8 | 8 |
| X/Y markers | 2 | 2 | 2 | 2 | 2 | 2 |
| Chr. 21 markers | 6 | 6 | 8 | 8 | 8 | 8 |
| Chr. 18 markers | 5 | 5 | 8 | 7 | 8 | 7 |
| Chr. 13 markers | 5 | 5 | 6 | 7 | 6 | 7 |
| Segmental Duplication | 2 | 2 | 8 | 3 | 8 | 3 |
| SMA Detection | No | ✓ | No | No | ✓ | ✓ |
| 5- or 6-dye system | 5 | 5 | 6 | 6 | 6 | 6 |
| Single tube multiplex | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Compatible with | Spectrum Compact CE from Promega, 3130/xl, 3500/xL and SeqStudio platforms | Spectrum Compact CE from Promega, 3130/xl, 3500/xL and SeqStudio platforms | Spectrum Compact CE from Promega, 3500/xL and SeqStudio platforms | Spectrum Compact CE from Promega, 3500/xL and SeqStudio platforms | Spectrum Compact CE from Promega, 3500/xL and SeqStudio platforms | Spectrum Compact CE from Promega, 3500/xL and SeqStudio platforms |
AneuQuick™ Max v2.2 is designed for 6-dye fragment analysis and is compatible with the following capillary electrophoresis platforms:
- Applied Biosystems™ 3500 Genetic Analyzer
- Applied Biosystems™ 3500xL Genetic Analyzer
- Applied Biosystems™ SeqStudio Genetic Analyzer
- Promega Compact Spectrum CE System
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