F8 Gene
To confirm the proper functioning of primers and other components forming the PCR and to verify the efficiency of the desired sequence amplification, a specific genotype-controlled DNA control can be used as a recognized indicator. In fact, DNA control can be used as a reference standard for assessing the quality control of the usual sample under investigation.
Given the importance of prenatal diagnosis in molecular genetics and the identification of various disease-causing mutations, the use of disease-specific DNA control is important both in direct genotype examination of the disease and in examining the SNP pattern in the genes under investigation in the RFLP method.
All DNA controls provided have been validated by sequencing or MLPA methods with optical absorption (OD) 2-1.7.
Features and Benefits:
- Used in PCR for various purposes
- For checking the presence or absence of PCR product
- Examination of DNA quality in terms of structure and degradation level
- Ideal for most standard genetic research programs
- Error prevention
- Possessing a genetic certificate
- Having normal, heterozygous, and/or homozygous genotypes
- Pattern for reliable amplification of long DNA fragments
- Southern hybridization analysis
- Genomic library construction
The Hem A gene, also known as the Factor VIII gene, is located on the X chromosome (Xq28). It encodes the coagulation factor VIII protein, which plays a crucial role in the blood clotting process. Factor VIII is essential for the formation of blood clots to stop bleeding.
KBC F8 Gene Control DNA- “K5612”- has an inversion 22/N. Inversion 22/N is a genetic mutation that involves the inversion of a segment of DNA within chromosome 22. This mutation can have implications for the hemoglobin A (Hem A) gene, which is responsible for producing a component of normal hemoglobin.
K5612 MSDS
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