IRFiling™ Globe Extra Kit v1.2

The KBC human identification profiling kits are used in various fields such as human identification, forensic medicine, parentage testing, kinship analysis, research, and so on.

Human identification profiling kits have been developed worldwide due to their extensive application in forensic genetics. These kits can be used to search databases and have high heterozygosity for most populations. Therefore, these kits can be used for various types of human identification, parentage testing, forensic medicine, and kinship studies. KBC HID kits are designed based on STR markers recommended by the European Network of Forensic Science Institutes (ENFSI), the National Institute of Standards and Technology (NIST), the International Society for Forensic Genetics (ISFG), and the Combined DNA Index System (CODIS).

DNA contains unique sequences of short tandem repeats (STRs) consisting of 3 to 7 base pairs scattered throughout the genome, which can be used for individual identification in forensic medicine. Since the exact number of repeats at each specific location varies among different individuals, forensic medicine can utilize these markers for identification purposes. Furthermore, each individual has two sets of STRs inherited from both parents, and each of these sets can have a different number of repeats at the same locus. In fact, a DNA profile is recognized as a DNA fingerprint that distinguishes individuals from each other and is only similar in identical twins.

The IRFiling™ Globe Extra v1.2 Kit is based on 29 markers, including 22 highly heterozygous STR markers, 2 gender determination markers and 4 Y-STR markers. 20 of these markers are designed based on CODIS. Additionally, 11 markers) also comply with the ESS or European standard, which ensures that the results obtained from this kit are internationally compliant and can provide responses with close to 100% accuracy in the shortest possible time. All 29 markers are amplified using the Multiplex PCR method, and their results are determined using capillary electrophoresis. The applications of the IRFiling™ Globe Extra v1.2 Kit include:

• Determination of kinship
• Human identity determination in accidents
• Criminal investigations
• Paternity and maternity testing
• Forensic genetics
• Determination of human profiles or patterns
• Population genetics and database creation

This kit can be used on DNA samples extracted from blood, amniotic fluid (AF), chorionic villus sampling (CVS), and DBC card (DNA Banking card produced by KBC), blood lysing buffer (BLB), amniotic fluid lysing buffer (AFL), and chorionic villus lysing buffer (CVL).

For more information about the product, its usage, and result analysis, please refer to the user manual.