How do DNA Banking Card works

 | Post date: 2017/01/7 | 

Biological samples, such as blood and saliva, adhere to the paper through the mechanism of entanglement, while the mixture of chemicals lyses cells and denatures proteins. Because nucleases are inactivated, the DNA is essentially stable when the sample is properly dried and stored. Nucleic acid damage from nucleases, oxidation, ultraviolet light (UV) damage, microbes, and fungus is reduced when samples are stored on the KBC card.

A marketable advantage of the KBC technology is that samples spotted on treated cards may be stored at room temperature. The chemicals on the KBC cards enhance the preservation of the DNA and inactivate many dangerous pathogens that may be found in liquid blood samples or dried biological stains. Because the cards are small in size , they are easily packaged, shipped, and stored for databasing.

Three options are available for DNA analysis with KBC cards: (1) direct amplification (no washing), (2) standard amplification (with washing; the so-called “punch-in” method—analyzing DNA while it is on the paper), and (3) extraction or purification of DNA from the card.



With KBC, the DNA remains tightly bound while proteins and inhibitors are washed from the matrix.

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